منابع مشابه
The future of exogenous surfactant therapy.
Since the identification of surfactant deficiency as the putative cause of the infant respiratory distress syndrome (RDS) by Avery and Mead in 1959, our understanding of the role of pulmonary surfactant in respiratory physiology and the pathophysiology of acute lung injury (ALI) has advanced substantially. Surfactant replacement has become routine for the prevention and treatment of infant RDS...
متن کامل[Exogenous surfactant therapy in pediatrics].
OBJECTIVE To review current knowledge about the use of exogenous surfactants in the treatment of different lung diseases causing acute respiratory failure in children. SOURCE OF DATA This review is based on the author's experience and on recent data retrieved from ONIA, Mdconsult, Medline and the Cochrane Database Library. SUMMARY OF THE FINDINGS In spite of the success of the use of exogen...
متن کاملExogenous surfactant therapy in newborn infants.
Exogenous surfactant therapy has an established role in the management of neonatal respiratory distress syndrome (RDS). This article summarises the current evidence on surfactant therapy. The use of surfactant for the treatment or prophylaxis of neonatal RDS results in a 30% to 65% relative reduction in the risk of pneumothorax and up to a 40% relative reduction in the risk of mortality. Advers...
متن کاملThe effectiveness and cost of exogenous pulmonary surfactant replacement therapy.
perception that we represented the regime and were its mouthpiece; that the situation was more sensitive than we had realised; that feelings of hurt and anguish ran deep; that we had in fact been resigned to accepting an atrocious situation. I apologised for this complacency, for the loss of dignity our colleagues had suffered for so long, and for all our errors of omis~ion, and expressed the h...
متن کاملExogenous surfactant therapy in 2013: what is next? who, when and how should we treat newborn infants in the future?
BACKGROUND Surfactant therapy is one of the few treatments that have dramatically changed clinical practice in neonatology. In addition to respiratory distress syndrome (RDS), surfactant deficiency is observed in many other clinical situations in term and preterm infants, raising several questions regarding the use of surfactant therapy. OBJECTIVES This review focuses on several points of int...
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ژورنال
عنوان ژورنال: Respiratory Care
سال: 2011
ISSN: 0020-1324,1943-3654
DOI: 10.4187/respcare.01306